1J1000 Real value prediction of accessible surface area in proteins
نویسندگان
چکیده
منابع مشابه
RVP-net: online prediction of real valued accessible surface area of proteins from single sequences
SUMMARY RVP-net is an online program for the prediction of real valued solvent accessibility. All previous methods of accessible surface area (ASA) predictions classify amino acid residues into exposure states and named them buried or exposed based on different thresholds. Real values in some cases were generated by taking the mid points of these state thresholds. This is the first method, whic...
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We present faster sequential and parallel algorithms for computing the solvent accessible surface area (ASA) of protein molecules. The ASA is computed by finding the exposed surface areas of the spheres obtained by increasing the van der Waals’ radii of the atoms with the van der Waals’ radius of the solvent. Using domain specific knowledge, we show that the number of sphere intersections is on...
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Direct prediction of protein structure from sequence is a challenging problem. An effective approach is to break it up into independent sub-problems. These sub-problems such as prediction of protein secondary structure can then be solved independently. In a previous study, we found that an iterative use of predicted secondary structure and backbone torsion angles can further improve secondary s...
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An accurate prediction of real value accessible surface area (ASA) from protein sequence alone has wide application in the field of bioinformatics and computational biology. ASA has been helpful in understanding the 3-dimensional structure and function of a protein, acting as high impact feature in secondary structure prediction, disorder prediction, binding region identification and fold recog...
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Knowing the structure of proteins is an essential step in developing new medicines. This is a very time consuming and expensive process. Researchers from many different areas are trying to find new and efficient ways to discovery protein structures. This is known as the Protein Structure Prediction (PSP) problem and it is divided into experimental and in silico methods [3]. In this work, we use...
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ژورنال
عنوان ژورنال: Seibutsu Butsuri
سال: 2002
ISSN: 0582-4052,1347-4219
DOI: 10.2142/biophys.42.s54_2